Wickham Chen, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1402. Fax: 214-768-3573. Email: [email protected] Tiankuan Liu, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1541. Fax: 214-768-4095. Email: [email protected] Junheng Zhang, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1402. Fax: 214-768-3573. Email: [email protected]...

Preterm neonates with respiratory distress syndrome (RDS) often develop a chronic form of lung disease called bronchopulmonary dysplasia (BPD), characterized by decreased alveolar and vascular development. Ventilator treatment with supraphysiological O2 concentrations (hyperoxia) contribute to the development of BPD. Hyperoxia down-regulates and hypoxia up-regulates many angiogenic factors in t...

Development of lung microvasculature is critical for distal airway formation. Both processes are arrested in the lungs of preterm newborns with bronchopulmonary dysplasia (BPD), a chronic form of lung disease. We hypothesized that activation of hypoxia-inducible factors (HIFs) augments lung vascular development. Pulmonary angiogenic factors were assessed by quantitative real-time PCR, Western b...

Wickham Chen, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1402. Fax: 214-768-3573. Email: [email protected] Tiankuan Liu, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1541. Fax: 214-768-4095. Email: [email protected] Ping Gui, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1733. Fax: 214-768-3573. Email: [email protected] Annie C...

Wickham Chen, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1402. Fax: 214-768-3573. Email: [email protected] Cheng-An Yang, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1641. Fax: 214-768-4095. Email: [email protected] Junheng Zhang, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1402. Fax: 214-768-3573. Email: [email protected]...

Bronchopulmonary dysplasia (BPD), a chronic lung disease affecting preterm neonates, is associated with significant childhood and adult health problems. Histopathologic features of BPD include impaired vascular and distal airway development. We previously showed that activation of hypoxia-inducible factors (HIFs) by inhibition of prolyl hydroxylase domain-containing proteins (PHDs) is feasible ...

Heavily doped compounds Mo3Sb7 xTex (x 1⁄4 0, 1.0, 1.4, 1.8) were synthesized by solid state reaction and sintered by spark plasma sintering. Both X-ray diffraction and electron probe microanalysis indicated the maximum solubility of Te was around x 1⁄4 1.8. The trends in the electrical transport properties can generally be understood using a single parabolic band model, which predicts that the...

Guojun Li, Zhigang Huang, Xingming Chen, Qingyi Wei Department of Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4095, USA Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030-4095, USA Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key ...